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FIT & DETOX

Piper nigrum 98%

Piperyna

Silnie skoncentrowany standaryzowany wyciąg z czarnego pieprzu będący źródłem aktywnej piperyny.

Kompleks zawiera najwyższą z dostępnych na rynku dawek czystej piperyny, która jest wspomagana przez kapsaicynę, forskolin i aloe vera.

PIPERYNA (Piper nigrum) - standaryzowany wyciąg z czarnego pieprzu będący źródłem 98% aktywnej piperyny. Piperyna to alkaloid występujący w wierzchniej warstwie czarnego pieprzu, któremu przypisujemy jego ostry i piekący smak. Jest substancją cenną ze względów zdrowotnych, wspomaga trawienie i kontrolę wagi ciała . W skład formuły wchodzą także dodatkowe ekstrakty dając kompleksowy produkt wspomagający odchudzanie.

KAPSAICYNA (Capiscum annum) - naturalna substancja ekstraktowana z pieprzu cayenne działa symbiotycznie z piperyną pobudzając spalanie tkanki tłuszczowej oraz węglowodanów.

FORSKOLIN (Coleus forskohli) - sproszkowany ekstrakt pokrzywy indyjskiej używany od tysięcy lat przez lekarzy ajurwedyjskich. Współcześnie wiadomo, że forskolin wspiera kontrolę wagi oraz inicjuje wzrost beztłuszczowej masy ciała.

ALOES ZWYCZAJNY (Aloe vera) - jedną z głównych korzyści ze spożywania aloesu jest wspomaganie i oczyszczanie układu trawiennego.

Skład Jedna kapsułka Dzienna porcja 3 kapsułki
Pieprz czarny - ekstrakt standaryzowany 25 mg 75 mg
w tym piperyna 98% 24,5 mg 73,5 mg
Pieprz cayenne - ekstrakt standaryzowany 100 mg 300 mg
w tym kapsaicyna 2% 2 mg 6 mg
Forskolin - ekstrakt 4:1 200 mg 600 mg
Aloes zwyczajny - ekstrakt 4:1 30 mg 90 mg
 

Producent: Biovitalic Sp. z o. o.

Suplement diety Piperyna, masa netto 42,6g. Opakowanie: 120 kapsułek.

Składniki: ekstrakt z forskolinu - pokrzywy indyjskiej (Coleus forskohli), ekstrakt z pieprzu cayenne (Capiscum annum) (w tym kapsaicyna), ekstrakt z aloesu zwyczajnego (Aloe vera), ekstrakt z pieprzu czarnego (Piper nigrum) (w tym piperyna), otoczka kapsułki - żelatyna.

ZALECANE SPOŻYCIE I PRZECHOWYWANIE

  • Zalecana dzienna porcja konieczna dla uzyskania korzystnego działania:
    3 kapsułki dziennie wraz z posiłkiem.
  • Zalecany jest zrównoważony sposób żywienia i zdrowy tryb życia.
  • Nie przekraczać zalecanej do spożycia dziennej porcji.
  • Produkt nie może być stosowany jako substytut zróżnicowanej diety i zdrowego stylu życia.
  • Nie stosować w przypadku uczulenia na którykolwiek ze składników.
  • W przypadku wystąpienia niepożądanych objawów należy przerwać stosowanie i skonsultować się z lekarzem.
  • W przypadku kobiet w ciąży, kobiet karmiących, lub osób stosujących leki - suplementacja powinna zostać skonsultowana z lekarzem.
  • Przechowywać w miejscu suchym, w temperaturze pokojowej, w miejscach niedostępnych dla małych dzieci.

 

1. Wspomaga trawienie
Zwiększa wydzielanie soków trawiennych (żołądkowego, trzustkowego i jelitowego) przyspieszając przemianę materii

2. Pomaga zwiększyć odporność
W tym także immunologię układu pokarmowego (GALT)

3. Pomaga osiągnąć lepszą sylwetkę
Wzmaga metabolizm przy równoczesnym podnoszeniu anabolizmu białek (przyswajanie białek, budowę tkanki łącznej właściwej i mięśniowej poprzecznie prążkowanej)

4. Detoksyfikacja
Pomaga oczyścić wątrobę i wspomaga jej funkcjonowanie

5. Wspomaga utratę wagi
Wpływa na stymulację spalania tłuszczu i węglowodanów

6. Naturalny antyoksydant
Wspiera hamowanie reakcji utleniania, a ściślej wydłużenie czasu inicjowania tego procesu. Przykładem może być opóźnianie oksydacji lipoprotein LDL, potocznie znanych jako „zły cholesterol”

7. Pomaga kontrolować wagę
Pomaga utrzymać wagę po schudnięciu - pozbyć się efektu jo-jo

8. Wzmacnia wchłanianie innych substancji
Istotnie zwiększa wchłanianie wielu składników odżywczych np. selenu, witamin z grupy B, beta-karotenu oraz koenzymu Q10 czy też kurkuminy

9. Pomaga przy dolegliwościach trawiennych
W medycynie chińskiej i indyjskiej była stosowana przy dolegliwościach trawiennych - zaparciach, biegunkach czy niestrawności. Poprawia strawność pokarmu i jego wykorzystanie

10. Reguluje naturalną gospodarkę
Normuje stężenie zdrowego poziomu glukozy

11. Wspiera zdrowie kobiecego układu rozrodczego
Pomaga oczyszczać narządy rozrodcze poprzez wspieranie krążenia krwi przez drobne naczynia krwionośne i kapilarne

12. Pobudza metabolizm
Pobudza transkrypcję genów białek związanych z procesem termogenezy i pomaga zapobiec akumulacji białej tkanki tłuszczowej - zapasowego źródła energii w organizmie

W mediach

Wkrótce
Badania

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metabolism disorder in HepG2 cells of insulin resistance models via targeting
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2: Dubey RK, Leeners B, Imthurn B, Merki-Feld GS, Rosselli M. Piperine Decreases 
Binding of Drugs to Human Plasma and Increases Uptake by Brain Microvascular
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3: Anissian D, Ghasemi-Kasman M, Khalili-Fomeshi M, Akbari A, Hashemian M, Kazemi
S, Moghadamnia AA. Piperine-loaded chitosan-STPP nanoparticles reduce neuronal
loss and astrocytes activation in chemical kindling model of epilepsy. Int J Biol
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4: Khalili-Fomeshi M, Azizi MG, Esmaeili MR, Gol M, Kazemi S, Ashrafpour M,
Moghadamnia AA, Hosseinzadeh S. Piperine restores streptozotocin-induced
cognitive impairments: Insights into oxidative balance in cerebrospinal fluid and
hippocampus. Behav Brain Res. 2017 Sep 20. pii: S0166-4328(17)31093-8. doi:
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5: Yang C, Bai J, Du SY, Cui YH, Zhang QS, Ma JM. [In vitro and in vivo
recoveries of cutaneous micro-dialysis probe of paeonol, eugenol and piperine].
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6: He H, Guo WW, Chen XQ, Zhao HY, Wu X. [Comparative metabolism of three amide
alkaloids from Piper longum in five different species of liver microsomes].
Zhongguo Zhong Yao Za Zhi. 2016 Aug;41(16):3084-3089. doi: 10.4268/cjcmm20161624.
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7: Shang Z, Cai W, Cao Y, Wang F, Wang Z, Lu J, Zhang J. An integrated strategy
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8: Cherniakov I, Izgelov D, Barasch D, Davidson E, Domb AJ, Hoffman A.
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Pharmacokinetic evaluation in healthy volunteers in comparison to buccal spray
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9: Dusane DH, Kyrouac D, Petersen I, Bushrow L, Calhoun JH, Granger JF, Phieffer 
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10: Singh S, Jamwal S, Kumar P. Neuroprotective potential of Quercetin in
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12: Caceres I, El Khoury R, Bailly S, Oswald IP, Puel O, Bailly JD. Piperine
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13: Syed SB, Arya H, Fu IH, Yeh TK, Periyasamy L, Hsieh HP, Coumar MS. Targeting 
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14: Alvarez-Berdugo D, Rofes L, Arreola V, Martin A, Molina L, Clavé P. A
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on swallowing dysfunction associated with aging and neurological diseases.
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15: Martinez-Sena MT, de la Guardia M, Esteve-Turrillas FA, Armenta S. Hard cap
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16: Park Y, Son JY, Lee BM, Kim HS, Yoon S. Highly Eribulin-resistant KBV20C Oral
Cancer Cells Can Be Sensitized by Co-treatment with the Third-generation
P-Glycoprotein Inhibitor, Elacridar, at a Low Dose. Anticancer Res. 2017
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17: Cherniakov I, Izgelov D, Domb AJ, Hoffman A. The effect of Pro
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oral bioavailability of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) 
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18: Panahi Y, Khalili N, Sahebi E, Namazi S, Reiner Ž, Majeed M, Sahbekar A.
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19: Beltrán LR, Dawid C, Beltrán M, Levermann J, Titt S, Thomas S, Pürschel V,
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20: Kim J, Lee KP, Lee DW, Lim K. Piperine enhances carbohydrate/fat metabolism
in skeletal muscle during acute exercise in mice. Nutr Metab (Lond). 2017 Jul
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21: Lu QY, Summanen PH, Lee RP, Huang J, Henning SM, Heber D, Finegold SM, Li Z. 
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22: Talib WH. Regressions of Breast Carcinoma Syngraft Following Treatment with
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23: Puiggalí-Jou A, Micheletti P, Estrany F, Del Valle LJ, Alemán C.
Electrostimulated Release of Neutral Drugs from Polythiophene Nanoparticles:
Smart Regulation of Drug-Polymer Interactions. Adv Healthc Mater. 2017 Sep;6(18).
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24: Yang JH, Mao KJ, Huang P, Ye YJ, Guo HS, Cai BC. Effect of piperine on the
bioavailability and pharmacokinetics of rosmarinic acid in rat plasma using
UPLC-MS/MS. Xenobiotica. 2017 Jul 3:1-8. doi: 10.1080/00498254.2017.1292564.
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25: Yasir A, Ishtiaq S, Jahangir M, Ajaib M, Salar U, Khan KM. Biology-Oriented
Synthesis (BIOS) of Piperine Derivatives and their Comparative Analgesic and
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26: Kumar A, Sasmal D, Sharma N. Mechanism of deltamethrin induced thymic and
splenic toxicity in mice and its protection by piperine and curcumin: in vivo
study. Drug Chem Toxicol. 2017 Feb 28:1-9. doi: 10.1080/01480545.2017.1286352.
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27: Shah UH, Patel S, Raval M. Stability Indicating Reverse Phase HPLC method for
estimation of Rifampicin and Piperine in Pharmaceutical Dosage Form. Curr Drug
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28: Zhang Y, Zhang J, Cui P, Zhang Y, Zhang W. Identification of Novel Efflux
Proteins Rv0191, Rv3756c, Rv3008, and Rv1667c Involved in Pyrazinamide Resistance
in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2017 Jul 25;61(8).
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29: Verma A, Kushwaha HN, Srivastava AK, Srivastava S, Jamal N, Srivastava K, Ray
RS. Piperine attenuates UV-R induced cell damage in human keratinocytes via
NF-kB, Bax/Bcl-2 pathway: An application for photoprotection. J Photochem
Photobiol B. 2017 Jul;172:139-148. doi: 10.1016/j.jphotobiol.2017.05.018. Epub
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30: Manayi A, Nabavi SM, Setzer WN, Jafari S. Piperine as a potential anti-cancer
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31: Piontek U, Wallaschofski H, Kastenmüller G, Suhre K, Völzke H, Do KT, Artati 
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32: Laha A, Sharma CS, Majumdar S. Sustained drug release from multi-layered
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33: Fan L, Cao X, Yan H, Wang Q, Tian X, Zhang L, He X, Borjihan G, Morigen. The 
synthetic antihyperlipidemic drug potassium piperate selectively kills breast
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34: Athukuri BL, Neerati P. Enhanced Oral Bioavailability of Domperidone with
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35: Chakraborty M, Bhattacharjee A, Kamath JV. Cardioprotective effect of
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37: Sawikr Y, Yarla NS, Peluso I, Kamal MA, Aliev G, Bishayee A.
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38: Siddiqui S, Ahamad MS, Jafri A, Afzal M, Arshad M. Piperine Triggers
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39: Thenmozhi K, Yoo YJ. Enhanced solubility of piperine using hydrophilic
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40: Zou X, Zou J, Yang L, Li G, Lu H. Thermal Rearrangement of Sulfamoyl Azides: 
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41: Dhiman P, Malik N, Khatkar A. Docking-related survey on Natural-product-based
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42: Hammad AS, Ravindran S, Khalil A, Munusamy S. Structure-activity relationship
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44: Mao K, Lei D, Zhang H, You C. Anticonvulsant effect of piperine ameliorates
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45: Delecroix B, Abaïdia AE, Leduc C, Dawson B, Dupont G. Curcumin and Piperine
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46: Gunasekaran V, Elangovan K, Niranjali Devaraj S. Targeting hepatocellular
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47: Ma ZG, Yuan YP, Zhang X, Xu SC, Wang SS, Tang QZ. Piperine Attenuates
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48: Hussain A, Rizwan-Ul-Haq M, Al-Ayedh H, Aljabr AM. Toxicity and
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50: Khawas S, Nosáľová G, Majee SK, Ghosh K, Raja W, Sivová V, Ray B. In vivo
cough suppressive activity of pectic polysaccharide with arabinogalactan type II 
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51: S C, B J, Mathew J, Radhakrishnan EK. Endophytic Phomopsis sp. colonization
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52: Thakur PS, Singh N, Sangamwar AT, Bansal AK. Investigation of Need of Natural
Bioenhancer for a Metabolism Susceptible Drug-Raloxifene, in a Designed
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53: Ngo QM, Tran PT, Tran MH, Kim JA, Rho SS, Lim CH, Kim JC, Woo MH, Choi JS,
Lee JH, Min BS. Alkaloids from Piper nigrum Exhibit Antiinflammatory Activity via
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55: Gong F, Cui L, Zhang X, Zhan X, Gong X, Wen Y. Piperine ameliorates
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Najczęstsze pytania

1. Jak piperyna może pomóc?

Piperyna w licznych badaniach wykazuje możliwość zwiększenia biodostępności innych składników odżywczych. Czarny pieprz oddziałuje z powierzchnią przewodu pokarmowego, zwiększając wchłanianie składników odżywczych, zwłaszcza selenu, witaminy B, beta-karotenu i kurkuminy.

 

2. Jakie są inne korzyści ekstraktu z czarnego pieprzu?

Jest on powszechnie znany jako przeciwutleniacz, a także może poprawić naturalny proces termogenezy w organizmie.

 

3. Czym jest termogeneza i dlaczego jest tak ważna?

Termogeneza jest procesem, w wyniku którego organizm wytwarza energię lub ciepło, zwiększając normalną metaboliczną zdolność do spalania tłuszczu. 

 

4. Od jak dawna używa się czarnego pieprzu w celach zdrowotnych ? 

Od wieków używano go na Bliskim Wschodzie. Czarny pieprz był używany w medycynie tradycyjnej, zwłaszcza w Chinach i Indiach,ze względu na jego korzyści zdrowotne. Delikatne ziarenka pieprzu są zazwyczaj zbierane tuż przed ich w pełnią dojrzałości,a następnie wysuszone pod słońcem w celu uzyskania optymalnej jakości ekstraktów.

 

5. Czy nie wystarczy spożyć czarnego pieprzu?

Badania wykazują,że oczyszczony ekstrakt w postaci stężonej piperyny ma znacznie większą aktywność niż w przypadku spożywania czarnego pieprzu. 

Ponadto aby uzyskać 1kg - 98% ekstraktu należy użyć aż do 60kg czarnego pieprzu. Aby uzyskać wskazane do spożycia ilości piperyny musielibyśmy spożywać ogromne ilości czarnego pieprzu dziennie.